How to upload a custom query signature.
Upload a custom query
To upload a custom query signature, click the toggle custom signature button, enter a name for the query, and click the upload button:
Requirements for uploaded custom query csv:1) first column is unique HGNC symbols2) either:- I. a column named dprime or logFC or- II. the second column contains effect size values
For custom queries, all uploaded genes that were also measured by L1000/CMAP02 are used. In contrast, query signatures from the Single-Cell or Bulk tabs use only the top 200 most differentially expressed genes.